Furosemide
Synonyms: furosemide, "Frusemide", "Lasix", "Furanthril", "Furosemid", "Errolon", "Fusid", "Frusemin", "Trofurit", "Rosemide", "Fuluvamide", "Desdemin", "Macasirool", "Fursemide", "Furantril", "Furanthryl", "Beronald", "Prefemin", "Lowpstron", "Aisemide", "Radonna", "Fulsix", "Transit", "Katlex", "Seguril", "Furesis", "Lasilix", "Lasex", "Salix", "Urex", "Frusetic", "Fursemid", "Eutensin", "Promedes", "Lazix", "Frusid", "Urosemide", "Profemin", "Furosedon", "Furanturil", "Frusemid", "Frusenex", "Rusyde", "Dryptal", "Yidoli", "Uremide", "Diural", "Impugan", "Uresix", "Aluzine", "Laxur", "Urian", "Disal", "Hydro-rapid", "Apo-Frusemide", "Synephron", "Spirofur", "Selectofur".
Source: Furosemide is a loop diuretic that is commonly used in the treatment of edematous states associated with cardiac, renal, hepatic failure and in the treatment of uncontrolled hypertension with abnormal renal function.
Identifiers:
IUPAC Name: 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid
CAS Number: 54-31-9
PubChem ID: 3440
InChiKey: ZZUFCTLCJUWOSV-UHFFFAOYSA-N
Canonical SMILES: C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)O)S(=O)(=O)N)Cl
Structural Properties:
Molecular Formula: C12H11ClN2O5S
Molecular Weight: 330.74
Pharmacophore Features:
Number of bond donors: 3
Number of bond acceptors: 7
Number of atoms different from hydrogen: 21
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Evidence Supporting This Chemical as an Emerging Contaminant
Olvera?Vargas, H., Oturan, N., Buisson, D., Van Hullebusch, E. D., & Oturan, M. A. (2015). Electro?Oxidation of the Pharmaceutical Furosemide: Kinetics, Mechanism, and By?Products.?CLEAN?Soil, Air, Water,?43(11), 1455-1463.