Lorazepam

Synonyms: lorazepam, "Ativan", "o-Chloroxazepam", "o-Chlorooxazepam", "Temesta", "Tavor", "Delormetazepam", "Lorabenz", "Idalprem", "Emotival", "Duralozam", "Bonatranquan", "Anxiedin", "Almazine", "Sedatival", "Laubeel", "Punktyl", "Orfidal", "Loraz", "Lorax", "Quait", "Wypax", "Apo-Lorazepam", "Lorazepam Intensol", "Norlormetazepam", "Aplacassee", "Silence", "Renaquil", "Loridem", "Lorenin", "Anzepam", "Lorsedal", "Lorazep", "Lorazene", "Equitam", "Aplacasse", "Tranqipam", "Sinestron", "Sedizepan", "Rocosgen", "Lorapam", "Sidenar", "Novhepar", "Lozepam", "Lorazin", "Larpose", "Kalmalin", "Efasedan", "Azurogen", "Donix", "Trapax", "Stapam", "Aripax", "Anxira"

Source: Lorazepam is an antianxiety agent used for the management of anxiety, insomnia, and chemotherapy-induced nausea and vomiting.

Identifiers:

IUPAC Name: 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number: 846-49-1
PubChem ID: 3958
InChiKey: DIWRORZWFLOCLC-UHFFFAOYSA-N
Canonical SMILES: C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl

Structural Properties:

Molecular Formula: C₁₅H₁₀Cl₂N₂O₂
Molecular Weight: 321,200

Pharmacophore Features:

Number of bond donors: 2
Number of bond acceptors: 3
Number of atoms different from hydrogen: 21

Downloads

2D structure (.sdf)
3D structure (.sdf)
3D structure (.mol2)
3D structure (.pdb)
3D structure (.pdbqt)

Search Similar molecules

Evidence Supporting This Chemical as an Emerging Contaminant

Banjac, Z., Ginebreda, A., Kuzmanovic, M., Marc?, R., Nadal, M., Riera, J. M., & Barcel?, D. (2015). Emission factor estimation of ca. 160 emerging organic microcontaminants by inverse modeling in a Mediterranean river basin (Llobregat, NE Spain). Science of the Total Environment, 520, 241-252.

External Links

PubChem

PubMed (general search)

PubMed (search as emerging contaminant)

2D-structure

3D-structure